Table 1.
Haemodynamic response to low-dose dobutamine and high-dose insulin infusion.
| LDD baseline | LDD peak | Difference | P | HDI baseline | HDI 60 min | Difference | P | |
|---|---|---|---|---|---|---|---|---|
| Heart rate (BPM) | 68±11 | 85±15† | 17±18 | 0.013 | 67±10 | 69±8 | 2±4 | 0.24 |
| Systolic BP (mmHg) | 126±12 | 173±19† | 47±17 | <0.001 | 122±9 | 128±13 | 6±9 | 0.08 |
| Diastolic BP (mmHg) | 74±8 | 73±7 | -1±9 | 0.73 | 72±7 | 76±10 | 4±7 | 0.13 |
| MAP (mmHg) | 92±7 | 106±7* | 15±10 | 0.002 | 89±6 | 93±10 | 4±7 | 0.08 |
| RPP (*103 mmHg/min) | 8.6±1.6 | 14.6±2.5† | 6.1±2.1 | <0.001 | 8.2±1.1 | 8.7±0.9 | 0.6±1.0 | 0.09 |
BPM=beats per minute, BP=blood pressure, MAP=mean arterial pressure, RPP=rate-pressure product, LDD=low-dose dobutamine, HDI=high-dose insulin. * p<0.05 compared with HDI 60 min, † p<0.01 compared with HDI 60 min.