Figure 4. Changes in selected genes in two day CD14 adherent monocytes after two hour FSH treatment (25 ng/ml).
The ordinate roughly correlates with transcript abundance. The data show 2–3 fold (note log scale) for increases in TNFα and TSG-6 mRNA after FSH treatment, and ~2-fold decrease in fibronectin. Cytoskeletal organizing proteins, including cofilin1 and filaminA, were modestly, ~40%, but consistently decreased. Multiple probes showed similar magnitude effects, except for TSG-6, for which only one probe-set was included in the array. For each measurement, n=20. All differences shown had p < 0.001 between untreated and FSH treated measurements in each pair.