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. Author manuscript; available in PMC: 2010 Apr 20.
Published in final edited form as: Dev Biol. 2007 May 24;308(2):593–605. doi: 10.1016/j.ydbio.2007.05.017

Figure 6. En and Slp regulate Ubx and abd-A independently.

Figure 6

Lateral views of stage 11 (A, B, C, E, F, G, H, I, J, and L) and stage 14 Drosophila embryos (D and K). A. PrdG4;UAS-Slp1;UAS-En embryos show that ectopic Slp1 (blue) represses abd-A (red) in the presence of En (green). B. PrdG4;UAS-Slp1;UAS-En embryos. Ectopic En (red) represses Ubx (green) in the presence of Slp1(blue). C and D. Ubx (green) and Abd-A (red) expression in en− slp− embryos. Note the loss in patterned abdominal Hox expression within en− slp− embryos compared to wild type embryos (see Fig 1C). E and F. en− slp−;PrdG4;UAS-En embryos demonstrates that ectopic En (blue) induces Abd-A (red in E) and represses Ubx (green in F). G and H. en− slp−;PrdG4;UAS-VP16En embryos. VP16En (blue) represses Abd-A (red in G) and stimulates Ubx (green in H) levels. I and J. en− slp−;PrdG4;UAS-Slp1 embryos show that ectopic Slp1 (blue) represses abd-A (red in I) and increases Ubx (green in J). K. Stage 14 en− slp−;PrdG4;UAS-Slp1 embryo. Where Slp1 represses abd-A, Ubx expression increases. L. Ubx− embryos have normal abd-A and slp1 expression, indicating that Slp1 does not require Ubx to repress abd-A.