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. 2010 Feb 3;285(15):11129–11142. doi: 10.1074/jbc.M109.087429

FIGURE 2.

FIGURE 2.

Altered spatial expression patterns of T-box genes in Pitx2 mutants. A–N, whole mount RNA in situ for T-box genes in WT (A, C, E, G, I, K, and M) and MUT (B, D, F, H, J, L, and N) E10.5 mice. A and B, Tbx1 expression in the foregut (asterisks) was higher in mutants. B, Tbx1 expression was higher in mutants. C and D, Tbx2 expression was higher in the somatopleure and limb mesenchyme of mutants. E and F, Tbx5 expression was higher in somatopleure (arrow) and intestine (asterisk) of mutants. G and H, Tbx6 expression was higher in somatopleure (arrow) and intestine of mutants. I and J, Tbx4 expression was lower in somatopleure (arrow) and intestine (asterisk) of mutants. K and L, Tbx15 expression was lower in the hindlimb margin (double arrows) and somatopleure of mutants. M and N, no alteration of Mga expression pattern was apparent.