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Fob1-dependent silencing at the end of rDNA array does not require replication fork protection proteins. A, schematic representation of the end of the rDNA array showing the mURA3 cassette. B, silencing of the mURA3 cassette in wild type, sir2Δ, fob1Δ, tof1Δ, and fob1Δcsm3Δ strains. C, silencing of the mURA3 cassette in wild type, fob1Δ, and csm3Δ strains. The csm3Δ strain was derived by complementing a fob1Δcsm3Δ doubly deleted strain with a CSM3-expressing plasmid.
