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Diagram of the miRNA binding sites within the SNCA 3′-UTR. A, two conserved sites, one for mir-7 and another for mir-153, are found in the SNCA 3′-UTR. B, bioinformatics prediction of miRNA and murine SNCA transcript interactions. C, predicted hybridization of miRNAs (gray) and SNCA (black) transcript using the RNAhybrid algorithm (36). The minimum free energy required for the hybridization is indicated.
