Table. Epidemiologic characteristics, strain identification, and treatment of 21 cases of American cutaneous leishmaniasis, French Guiana, 2004–2005*.
Case no. | Primary infection |
Leishmaniasis recidiva cutis |
|||||||
---|---|---|---|---|---|---|---|---|---|
Lesion(s), location (no.) | PI treatment† | Time to healed lesions, mo | Disease-free interval, mo | Direct examination | Strain identification | PI treatment | Outcome | ||
1 | Thorax (1) | IV, 4 mg/kg on alternate days × 3 | 1 | 4 | + | Leishmania guyanensis MON-45 | IV, 4 mg/kg on alternate days × 4 | Cured | |
2 | Right forearm (1) | IV, 4 mg/kg on alternate days × 3 | 3 | 6 | + | L. guyanensis MON-45 | IV, 4 mg/kg on alternate days × 4 | Cured | |
3 | Left leg (1) and chin (3) | IV, 4 mg/kg on alternate days × 3 | 1 | 4 | + | Negative culture | IV, 4 mg/kg on alternate days × 4 | Cured | |
4 | Chin (3) | IV, 4 mg/kg on alternate days × 3 | 1 | 4 | + | Negative culture | IV, 4 mg/kg on alternate days × 4 | Cured | |
5 | Behind left ear (1) | IV, 4 mg/kg on alternate days × 3 | 1 | 3 | + | L. guyanensis MON-131 | IV, 4 mg/kg on alternate days × 4 | Cured | |
6 | Left ear (1) | IV, 4 mg/kg on alternate days × 3 | 1 | 6 | + | Negative culture | IV, 4 mg/kg on alternate days × 4 | Cured | |
7 | Right ankle (5) | IV, 4 mg/kg on alternate days × 3 | 2.5 | 4 | + | Negative culture | IV, 4 mg/kg on alternate days × 4 | Cured | |
8–21 | Various | IV, 4 mg/kg on alternate days × 3 (for 9 patients) or IM, 4 mg/kg on alternate days × 2 (for 5 patients)† | 1–3 | – | – | – | – | – |
*PI, pentamidine isethionate; IV, intravenous; IM, intramuscular. †IV versus IM administration of pentamidine isethionate was not associated with recurrent forms.