Skip to main content
. Author manuscript; available in PMC: 2010 Apr 20.
Published in final edited form as: N Engl J Med. 2009 May 20;360(24):2544–2555. doi: 10.1056/NEJMoa0810440

Figure 2. Results of the Genomewide Association Analysis.

Figure 2

The y axis represents the level of significance (from the EIGENSTRAT method) for each single-nucleotide polymorphism on each chromosome along the x axis. The dotted line indicates the threshold for genomewide association significance.21 The P values were adjusted in EIGENSTRAT for the 10 eigenvectors having the highest eigenvalues. HLA-DQB1 denotes the gene encoding major histocompatibility complex class II DQ β chain 1, IL12A the gene encoding interleukin-12α, IL12RB2 the gene encoding interleukin-12 receptor β2, and STAT4 the gene encoding signal transducer and activator of transcription 4.