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. Author manuscript; available in PMC: 2010 Apr 20.
Published in final edited form as: Cell Death Differ. 2008 Dec 19;16(3):475–482. doi: 10.1038/cdd.2008.181

Figure 1. Caspase dependent cell death is an infrequent event in prostatic acini.

Figure 1

A. BPH-1 cells were grown in Matrigel for the indicated number of days. Acini were fixed and stained for active caspase 3 (green) or PSA (green), nuclei were counterstained with DAPI. Representative images are shown that cross section through the middle of acini. Arrows indicate the edge of the forming lumen. The experiments shown are representative of a minimum of three replicates.

B. Transmission electron microscopy of a BPH-1 acinus grown in Matrigel for 7 days.

C. and D. Representative image of Hela (C) and MCF-10A 9 (D) cells grown in Matrigel for 7 days, fixed and stained for active caspase 3 (green) and LC-3 (red). Nuclei were counterstained with DAPI (blue). All bars indicate 50 μm.