Table 4.
Summary of the significant core regions containing known genes in the Andean population for the WGLRH test
Chromosome | SNPs in core region | Haplotype frequency | p-value adjusted | Genes in core region* |
---|---|---|---|---|
1 | 3 | 0.060 | 0.032 | KCNK2 |
1 | 2 | 0.080 | 0.038 | KCNK2 |
1 | 5 | 0.070 | 0.050 | KIAA1026 |
1 | 7 | 0.070 | 0.032 | PEX14 |
2 | 2 | 0.520 | 0.016 | ERBB4 |
2 | 2 | 0.540 | 0.006 | INPP5D |
2 | 2 | 0.080 | 0.038 | TMEM169 |
3 | 2 | 0.330 | 0.011 | CPNE4 |
4 | 2 | 0.051 | 0.007 | LDB2 |
4 | 3 | 0.090 | 0.000 | RBM47 |
5 | 7 | 0.070 | 0.034 | FCHO2 |
6 | 3 | 0.120 | 0.018 | F13A1 |
6 | 4 | 0.080 | 0.001 | F13A1 |
6 | 3 | 0.120 | 0.036 | KCNK5 |
8 | 2 | 0.130 | 0.036 | ADRA1A |
9 | 2 | 0.176 | 0.047 | ADAMTSL1 |
9 | 2 | 0.610 | 0.044 | PTPRD |
9 | 3 | 0.070 | 0.011 | VAV2 |
10 | 2 | 0.170 | 0.015 | AK056561 |
10 | 2 | 0.500 | 0.021 | FAM107B |
10 | 2 | 0.101 | 0.040 | GFRA1 |
10 | 3 | 0.540 | 0.023 | OLAH |
11 | 2 | 0.090 | 0.047 | LDLRAD3 |
11 | 3 | 0.060 | 0.002 | PSMD13 |
12 | 2 | 0.330 | 0.032 | CHST11 |
12 | 5 | 0.080 | 0.035 | SLC4A8 |
14 | 7 | 0.080 | 0.002 | KCNK10 |
14 | 3 | 0.440 | 0.043 | PPP2R5C |
17 | 2 | 0.390 | 0.036 | C17orf54 |
17 | 6 | 0.080 | 0.003 | MPRIP |
18 | 2 | 0.450 | 0.038 | PTPRM |
19 | 2 | 0.295 | 0.002 | GNA15 |
20 | 2 | 0.100 | 0.000 | RP5-1022P6.2 |
21 | 2 | 0.490 | 0.001 | ERG |
Core regions that do not contain a known gene are not listed.
*Genes are listed for the core region only and not the 500 kb extended haplotype regions identified by each core.