Table 2.

Effect of three types of care for cystic fibrosis on outcome measures^* (P value represents any difference between the three groups. Adjusted mean calculated after correction for imbalances of important covariates between groups)

Outcome measure	Group A (n=50)	Group B (n=47)	Group C (n=36)	P value
FEV1 (body mass index as covariate):
Observed mean	60.5	53.1	44.5
Adjusted mean	53.5	53.9	50.7	0.777
Pooled within group SD	19.35
FEV1(without body mass index):
Adjusted mean	61.2	54.3	42.6	0.002
Pooled within group SD	22.26
Body mass index (with FEV1 as covariate):
Observed mean	21.3	20.2	18.3
Adjusted mean	21.2	20.0	18.8	<0.001
Pooled within group SD	2.02
Body mass index (without FEV1):
Adjusted mean	21.6	20.0	18.3	<0.001
Pooled within group SD	2.39
Chest x ray film score†:
Median (interquartile range)	9.0 (6.0-11.0)	10.0 (7.0-12.8)	12.0 (10.0-13.0)	0.003
	n=47	n=44	n=33
Age (years) at colonisation with Pseudomonas aeruginosa‡:
Observed mean (SD)	11.1 (5.5)	18.1 (7.3)	16.1 (9.5)	<0.001
	n=41	n=36	n=19

FEV₁ Forced expiratory volume in one second as percentage of predicted values. ^*Group A patients had had both paediatric and adult care in a cystic fibrosis centre; group B patients had not had paediatric but had had adult care in a cystic fibrosis centre; group C patients had had no care in a cystic fibrosis centre. ^†Kruskal-Wallis test. ^‡One way analysis of variance.