Table 3.

Allele and Genotype Frequencies for the rs2268458 SNP of TSHR Gene in GO Patients

Allele/genotype	Controls (n = 118)	GO (n = 120)	GO vs. controls p-value (OR)	Non-GO (n = 80)	Non-GO vs. controls p-value (OR)
T	185 (78.4%)	177 (73.8%)	0.236 (1.3)	108 (67.5%)	0.015 (1.7)
C	51 (21.6%)	63 (26.3%)		52 (32.5%)
TT	78 (66.1%)	67 (55.8%)	0.166	38 (47.5%)	0.031
TC	29 (24.6%)	43 (35.8%)		32 (40.0%)
CC	11 (9.3%)	10 (8.3%)		10 (12.5%)
TT vs. CC + TC			0.105 (1.5)		0.009 (2.2)
CC vs. TT + TC			0.788 (1.1)		0.476 (1.4)

The numbers represent individual subjects or alleles, with the percentage in parentheses.

GO, Graves' ophthalmopathy; OR, odds ratio.