Table 2.
Adjusted Odds Ratios and 95% Confidence Intervals for Clinical Breast Examinations (CBEs) in Past 5 Years (1990–1994) in DES-Exposed and Unexposed Women Aged 40–49
|
DES exposed (n = 563) |
DES unexposed (n = 232) |
|
|
|
||
---|---|---|---|---|---|---|---|
n | % | n | % | Adjusted ORa,b | 95% CIa | p for trendc | |
Number of CBEs in past 5 yearsd | |||||||
Missinge | 4 | 0.7 | 2 | 0.9 | |||
None | 18 | 3 | 8 | 3 | |||
Once | 46 | 8 | 22 | 10 | |||
2–3 timesf | 149 | 27 | 60 | 26 | 1.00 | Referent | |
4–5 timesg | 255 | 45 | 116 | 50 | 0.97 | 0.68–1.37 | |
>5 timesh | 91 | 16 | 24 | 10 | 1.67 | 0.95–2.96 | 0.39 |
Reported history of BBDa(n = 252) | |||||||
---|---|---|---|---|---|---|---|
|
DES exposed (n = 173) |
DES unexposed (n = 79) |
|
|
|
||
n | % | n | % | Adjusted ORa,b | 95% CIa | p for trendc | |
Number of CBEs in past 5 yearsd | |||||||
None | 1 | 0.6 | 2 | 3 | |||
Once | 11 | 6 | 6 | 8 | |||
2–3 timesf | 37 | 21 | 15 | 19 | 1.00 | Referent | |
4–5 timesg | 86 | 50 | 45 | 57 | 0.87 | 0.44–1.70 | |
>5 timesh | 38 | 22 | 11 | 14 | 0.83 | 0.29–2.35 | 0.52 |
Reported No history of BBDa(n = 533) | |||||||
---|---|---|---|---|---|---|---|
|
DES exposed (n = 382) |
DES unexposed (n = 151) |
|
|
|
||
n | % | n | % | Adjusted ORa,b | 95% CIa | p for trendc | |
Number of CBEs in past 5 yearsd | |||||||
None | 17 | 5 | 6 | 4 | |||
Once | 35 | 9 | 16 | 11 | |||
2–3 timesf | 110 | 29 | 45 | 30 | 1.00 | Referent | |
4–5 timesg | 168 | 44 | 71 | 47 | 1.08 | 0.70–1.65 | |
>5 timesh | 52 | 14 | 13 | 9 | 2.20 | 1.04–4.67 | 0.36 |
OR, odds ratio; CI, confidence interval; BBD, benign breast disease.
Adjusted for age (continuous variable), education, marital status, and site.
The p value (two-sided) for trend included all five outcome frequency categories; none of the frequency categories were combined for the trend test.
Five years [(1994–birth year) − 5] were subtracted from the current questionnaire age to put the women's respective screening age in the proper context of the previous 5 years: no women >age 50 were present in the dataset, and only 20% were aged 40–49.
Missing values indicate a nonresponse to the question regarding number of CBEs in the past 5 years.
Categories (none, once, and 2–3 times) were combined to form the reference category.
The category 4–5 times was compared to the reference group and defined as compliant for CBE screening for this age group.
The category >5 times was compared to the reference group and defined as exceeding recommendations for CBE screening for this age group.