Table 3.

Association between baseline OH and poor cognitive function at the ARIC visit 2 examination (OR, with 95% CI in parentheses)

Covariates included	Delayed word recall	Digit symbol substitution	Word fluency
(1) Age	1.18 (0.98–1.42)	1.34 (1.12–1.62)	1.25 (1.03–1.51)
(2) Model 1 + race/center, gender and education	1.11 (0.92–1.35)	1.15 (0.93–1.43)	1.12 (0.93–1.37)
(3) Model 2 + systolic BP and antihypertensive medications	1.11 (0.92–1.34)	1.16 (0.93–1.43)	1.10 (0.91–1.34)
(4) Model 3 + selected risk factors and conditions	1.07 (0.86–1.32)	1.17 (0.93–1.48)	1.09 (0.88–1.35)

Poor cognitive function defined as performance in the lowest quintile on the test. Risk factors in model 4: current drinking, current smoking, diabetes mellitus, carotid intima-media thickness, low ankle-brachial index, low-density lipoprotein cholesterol, resting heart rate, prevalent CHD, cancer and fair/poor self-reported health.