Figure 3. Transcriptional changes in Armigeres subalbatus when comparing a Brugia pahangi- vs. a Brugia malayi-infected bloodmeal.

The bar graph represents the number of genes with a significant fold difference between B. pahangi- or B. malayi-exposed mosquitoes. Volcano plots were used to create working gene lists to identify transcripts associated with B. pahangi development (left) vs. B. malayi resistance (right). At 1, 6, 12, 24 h post infection and 2–3 d post challenge there were 10, 14, 15, 27, and 4 detectable transcripts, respectively, more associated with B. pahangi infection. Following the same time course, there were 63, 20, 57, 81, and 6 detectable transcripts, respectively, more associated with B. malayi resistance. The bar graph represents groups of mosquitoes that included those exposed to blood containing B. pahangi mf and those exposed to blood containing B. malayi mf. Significant increases or decreases in transcript abundance cannot be delineated.