Table 3.
Summary of MCSBE simulations showing the average lifetime MutS spends on the DNA (Figure 8C) as well as the total number of conformational transitions and states sampled in a single binding event for a given initial state in the simulation.
| MCSBE initial state | |||||||
|---|---|---|---|---|---|---|---|
| U | U* | I | B* | B | SB |
Average at equilibrium |
|
| Residence time on the DNA | 38.80 | 37.81 | 29.82 | 30.33 | 41.44 | 46.50 | 38.61 |
|
# conformational transitions in SBE |
4.97 | 4.94 | 3.60 | 4.34 | 4.19 | 4.96 | 4.28 |
|
# unique states sampled in SBE (including the initial state) |
2.91 | 3.12 | 2.45 | 2.85 | 2.43 | 3.05 | 2.59 |