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Cytotoxicity of 1 and 2 Against a Panel of Cancer Cell Lines.
| IC50 (µM) | ||
|---|---|---|
| Cyclic DMMC (1) | Linear DMMC (2) | |
|
HCT-116 human colon carcinoma |
0.020 | 0.016 |
|
H-460 human large cell lung carcinoma |
0.063 | 0.094 |
|
MDA-MB-435 human carcinoma |
0.22 | 0.23 |
|
Neuro-2A murine neuroblastoma |
> 1.0 | > 1.0 |
