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A comparison of electrophysiological data from α1β3γ2 and α6β3γ2 using bath-applied PRO or TCEt, picospritzer-applied GABA (values are pooled means ± SEM, 4 ≤ n ≤ 15)
| Anesthetic | Cell line | EC50 | Hill coefficient | Maximum (% enhancement) |
|---|---|---|---|---|
| PRO | α1β3γ2 | 2.6 ± 0.5 μM | 1.3 ± 0.2 | 564 ± 53 |
| α6β 3γ2 | 4.6 ± 1.9 μM | 1.3 ± 0.3 | 136 ± 17 | |
| TCEt | α1β3γ2 | 0.8 ± 0.2 mM | 1.0 ± 0.6 | 258 ± 21 |
| α6β 3γ2 | 0.6 ± 0.2 mM | 1.3 ± 0.3 | 60 ± 3 |
