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. Author manuscript; available in PMC: 2010 Apr 21.
Published in final edited form as: Cancer Gene Ther. 2009 Oct 16;17(4):266–274. doi: 10.1038/cgt.2009.71

Figure 1.

Figure 1

Infectability of schwannomas in culture and in vivo with HSV amplicon vector. (a) HEI-193 cells were infected with HGC-Fluc HSV amplicon vector. Forty-eight hours later, cells were monitored for GFP fluorescence. (b) Five million HEI-193 cells were implanted subcutaneously into both flanks of nude mice. After 1 week, tumors were injected with 15 µl 107 tu HGC-Fluc vector. Twenty-four hours later, mice were injected with d-luciferin and imaged for Fluc activity using a CCD camera. (c–d) Tumors in (b) were removed 48 h post-injection and processed for GFP fluorescence (green) and S100 immunofluorescence staining (red). Scale bars: a, 100 µm; b, 20 µm. (See online version for color figure)