TABLE III.

Other Immunologic Tests in Patients and Controls

	VHL598C>T homozygotes (N = 30)	VHL normal alleles (N = 30)	P*
Serum globulins (g/L)
α1 globulin	2.6 (2.3–2.8)	2.6 (2.4–2.8)	0.9
α2 globulin	7.4 (7.0–8.1)	7.2 (6.3–8.1)	0.4
β globulin	10.3 (9.5–11.4)	9.6 (9.2–10.8)	0.06
γ globulin	15.9 (13.5–16.7)	15.6 (13.5–17.6)	0.8
Lymphocyte subsets (103/mm3)
CD3	1.3 (1.2–1.5)	1.5 (1.2–1.7)	0.09
CD4	0.7 (0.5–0.8)	0.8 (0.7–1.1)	0.012
CD8	0.6 (0.6–0.7)	0.6 (0.5–0.8)	0.7
CD4/CD8 ratio	1.1 (0.9–1.3)	1.4 (1.1–1.6)	0.015
CD19 (B-lymphocyte marker)	0.3 (0.2–0.4)	0.3 (0.2–0.5)	0.6
CD16 (NK cell marker)	0.4 (0.3–0.6)	0.4 (0.2–0.5)	0.2
CD95 (apoptosis marker)	0.07 (0.04–0.13)	0.06 (0.04–0.09)	0.2
Other tests
Circulating immune complexes	26 (18–50)	41 (26–65)	0.2
IgG (g/L)	14.3 (11.8–18.6)	16.6 (12.7–22.1)	0.2
IgA (g/L)	2.3 (1.8–2.9)	1.9 (1.7–2.4)	0.1
IgM (g/L)	1.8 (1.4–2.2)	1.7 (1.2–2.1)	0.3

Results in median and interquartile range