Figure 1.

Human leukocyte antigen-G (HLA-G) expression in patients with invasive cervical carcinoma (ICC). Cervical biopsies obtained from patients according to the presence of ICC with metastasis (ICC^W) or ICC without metastasis (ICC^WT) were analyzed by immunohistochemistry. (A) HLA-G expression in trophoblast tissue obtained from a recent abortion (positive control). (B) Absence of anti-HLA-G 5A6G7, negative control. (C) Normal cervix from a healthy woman (autopsy). Note the absence of staining in squamous epithelial cells. (D) Intense HLA-G staining in ICC; and (E) intense HLA-G staining in lymph node metastasis. Bars: A,B = 250 μm; C–E = 100 μm.