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. 2010 Mar 26;2:21. doi: 10.1186/1758-5996-2-21

Table 1.

Association between several medical conditions and visfatin

Medical Condition Visfatin
Atherosclerosis Increased serum levels [10,31]
Increased expression in instable plaques [31]

Endothelial dysfunction Increased serum levels [18]

Cardioprotection Reduces infarct area [36]

Metabolic Syndrome Controversial, Increased serum levels [34]

Adiponectin Controversial [18,27]

Hepatic Fat Disease Diminished serum levels in steatohepatitis [16]
Increased serum levels with progressive portal inflammation [17]

Tumoral replication Visfatin antagonist being tested [19]

Acute lung injury Increased serum levels [15]

Renal insufficiency Increased serum levels [18]

Beta cell function impairment Increased serum levels [10,22,23,28,29]

Insulin resistance No correlation [20,22,23]

Insulin-mimetic effect Controversial, no effect [5,10,15-20,22-24,27-29]

Diabetes Controversial [18,23,27,28]

Obesity Increased serum levels [20,22]

Visceral Fat Controversial, no correlation [5,15-20,27]

Vascular smooth muscle Promotes inflammation [32]