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. 2010 Feb 11;59(5):1143–1152. doi: 10.2337/db09-0807

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© 2010 by the American Diabetes Association.

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FIG. 5. — Pancreatic islet sizing in VIP knockout (KO) and wild-type (WT) mice. Representative pancreatic islets from wild-type (A) or VIP knockout (B) mice demonstrate similar insulin (red fluorescence) and glucagon (green fluorescence) expression profiles. C: Mean islet area (mm²) measured in wild-type or VIP knockout pancreata. D: Similar mean α-cell (α) and β-cell (β) percentage in the islets of VIP knockout and wild-type mice. E: Relative distribution of the different islet sizes (1 = small; 2 = middle; 3 = large) for VIP knockout and wild-type mice. Values are expressed as the means ± SEM. (A high-quality digital representation of this figure is available in the online issue.)