Table 2.
SARC | HP | HC | |
---|---|---|---|
Characteristics | (n = 23) | (n = 7) | (n = 24) |
Total BALF cells (×104/ml) | 31·1 (9·9–65·0)* | 26·2 (5·1–102·9)‡ | 10·1 (4·3–16·3) |
Cell types: | |||
Alveolar macrophages % | 65·2 (13·4–84·6)* | 67·6 (8·5–79·7)* | 87·1 (56·3–96·8) |
(×104/ml) | 16·0 (6·8–34·5)* | 9·8 (4·0–21·2) | 8·2 (3·9–15·8) |
Lymphocytes % | 47·0 (15·0–83·0)* | 37·0 (31·0–80·0)* | 9·6 (2·3–39·9) |
(×104/ml) | 11·2 (1·5–54·0)* | 9·9 (1·8–82·3)* | 0·9 (0·3–5·4) |
Neutrophils % | 1·1 (0·1–2·4)‡ | 1·9 (0·5–4·7) | 1·6 (0·1–8·1) |
(×104/ml) | 0·3 (0·02–1·0) | 0·8 (0·07–2·0) | 0·2 (0·0–0·8) |
Eosinophils % | 0·5 (0·1–4·1) | 0·7 (0·1–3·0) | 0·3 (0·0–4·1) |
(×104/ml) | 0·1 (0·01–0·7)† | 0·3 (0·01–0·9)† | 0·03 (0·0–0·4) |
BALF CD4/CD8 cell ratio | 3·6 (0·5–25·2)* | 0·8 (0·6–6·3) | 1·1 (0·2–11·0) |
Total PB cells (×106/ml) | 5·6 (3·2–14·4)§ | 7·7 (6·5–11·2) | 5·8 (3·2–9·0)§ |
Lymphocytes % | 23·0 (11·0–44·0)* | 25·0 (20·0–36·0) | 33·5 (20·6–49·9) |
(×106/ml) | 1·3 (0·4–2·5) | 1·8 (1·4–3·2)¶ | 1·9 (1·3–2·8)¶ |
PB CD4/CD8 cell ratio | 1·2 (0·4–3·3)‡ | 2·0 (0·6–4·0) | 1·8 (0·9–5·8) |
Significantly different from healthy controls (HC):
P < 0·001;
P < 0·01;
P < 0·05. Significantly different from hypersensitivity pneumonitis (HP):
P < 0·05. Significantly different from sarcoidosis (SARC);
P < 0·01. Numbers are presented as median (range). BALF: bronchoalveolar lavage fluid.