Figure 1.
Virus-binding antibody responses induced to VEEV TrD virus by vaccination with fV3526 formulated with the indicated adjuvant and C84. Sera were obtained from mice on Day 49 post-primary vaccination. These data are reported as the geometric mean endpoint titers as determined by ELISA. Black bars: IM vaccinated, Gray bars: SC vaccinated. C84 administered IM was not evaluated. *statistically different from fV3526/CpG administered IM (p<0.05) **statistically different from all other groups (p<0.01). The titers presented are combined titers from similarly vaccinated mice (same route, same formulation) giving a total of 20 mice per group. Groups were later split into 10 mice challenged by the aerosol route and 10 challenged by the SC route.
