Table 4.

Adjusted means and 95% confidence intervals of diastolic function parameters by the presence of hypertension and/or diabetes

	HT−/DM−	HT	DM	HT + DM
E-wave (cm/s)	70.9 (68.2–73.5)	68.7 (66.9–70.6)	71.3 (65.5–77.0)	73.7 (71.1–76.4)‡
A-wave (cm/s)	85.6 (82.7–88.6)	86.8 (84.7–88.9)	92.7 (86.3–99.1)*	92.6 (89.6–95.6)**‡
E/A ratio	0.86 (0.82–0.91)	0.83 (0.79–0.86)	0.79 (0.69–0.89)	0.84 (0.79–0.89)
E′-wave (cm/s)	7.9 (7.6–8.1)	7.2 (7.0–7.4)**	7.6 (7.0–8.1)	7.2 (6.9–7.4)**
E/E′ ratio	9.6 (9.1–10.0)	10.2 (9.8–10.5)*	10.0 (9.1–11.0)	11.1 (10.7–11.6) **‡§

HT−/DM−, absence of hypertension and diabetes; HT, hypertension only; DM, diabetes only; HT + DM, hypertension and diabetes. Standard set of covariates: age, BMI, sex, LV mass index, LV relative wall thickness, LV ejection fraction, and heart rate.

*P < 0.05 and **P < 0.01 vs. HT−/DM−.

^‡P < 0.01 vs. HT.

^§P < 0.05.