Table 1. Baseline Comparison of HIV-Infected Participants a.
| WIHS | MACS | |
|---|---|---|
| Number of participants | 1574 | 955 |
| Number of paired visits | 8253 | 2919 |
| Age category, % | ||
| <40 years | 56.6 | 29.2 |
| 40 - 50 years | 34.5 | 46.3 |
| ≥50 years | 8.9 | 24.5 |
| Race/ethnicity, % | ||
| African American | 55.8 | 26.4 |
| Hispanic | 30.0 | 12.6 |
| Caucasian | 14.2 | 61.1 |
| Baseline education | ||
| < High school education | 38.4 | 6.8 |
| Completed high school | 29.4 | 17.2 |
| > High school education | 32.2 | 76.0 |
| Alcohol consumption | ||
| none | 59.9 | 23.4 |
| 1 drink/week | 18.4 | 28.7 |
| ≥2 drink/week | 21.7 | 47.9 |
| Baseline CES-D score ≥16 | 51.1 | 27.6 |
| Body Mass Index | ||
| <24.9 | 37.3 | 56.1 |
| 25.0-29.9 | 32.7 | 35.2 |
| ≥30.0 | 30.1 | 8.7 |
| Prior diagnosis of AIDS, % | 36.5 | 15.6 |
| Mean CD4+ cell count, cells/μl | 438.2 | 526.0 |
| Mean log HIV RNA, copies/ml | 7.1 | 5.7 |
| Mean years since HAART initiation | 2.4 | 3.8 |
| Pattern of HAART use | ||
| Stable use | 54.7 | 62.9 |
| Switched regimens | 14.7 | 18.3 |
| Discontinue some ARVs | 24.8 | 14.1 |
| Discontinue all ARVs | 5.8 | 4.6 |
| HAART class | ||
| No ARVs | 16.9 | 9.2 |
| PI-containing | 43.1 | 50.1 |
| PI-sparing | 39.9 | 40.7 |
ARV = antiretrovirals; CES-D = Center for Epidemiological Studies Depression; HAART = highly-active antiretroviral therapy; PI = protease inhibitor.
a
All comparisons by cohortwere P<0.001 using Pearson’s Chi-square test for categorical variables and Wilcoxon rank-sum test for continuous variables.