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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: J Immunol. 2009 Dec 9;184(2):796–806. doi: 10.4049/jimmunol.0901748

FIGURE 1.

FIGURE 1

Lymphadenopathy, splenomegaly and lymphocyte activation is reduced in IRF5-deficient RII.Yaa mice. A, Lymph node and spleen weights from Irf5+/+ (n = 12), Irf5+/− (n = 12), and Irf5−/− (n=14) RII.Yaa mice and wildtype (WT) mice (n=12) were measured at 5 months of age. Representative spleens are shown in panel on right. B and C, CD69 and CD44 expression on splenic T cells (B) and B cells (C) from 5 month old Irf5+/+ (n = 6), Irf5+/− (n = 10), and Irf5−/− (n=9) RII.Yaa mice and wildtype (WT) mice (n=11). Data are presented as mean ± SEM. *, p < 0.05; **, p< 0.01; ***, p < 0.001; ****, p < 0.0001 by Mann-Whitney U test.