Table 1.
Cryotherapy* | LEEP* | |||
---|---|---|---|---|
n | (%) | n | (%) | |
Indications/contraindications** | ||||
Restrictions based on lesion size and extension | 8 | (72.7) | 0 | (0.0) |
Transformation zone entirely visible | 6 | (54.5) | 2 | (12.5) |
No evidence of invasive disease | 6 | (54.5) | 5 | (31.3) |
No history of screening or treatment for CIN | 7 | (63.6) | 2 | (12.5) |
No gynecologic abnormality† | 4 | (36.4) | 1 | (6.3) |
No severe cervicitis | 1 | (9.1) | 2 | (12.5) |
Restrictions for pregnant women†† | 6 | (54.5) | 3 | (18.8) |
Contraindication to cryotherapy | 0 | (0.0) | 5 | (31.3) |
Enrollment** | ||||
Community outreach | 7 | (63.6) | 4 | (25.0) |
Primary care/local health centers | 3 | (27.3) | 1 | (6.3) |
Gynecologic clinic/tertiary care | 3 | (27.3) | 10 | (62.5) |
Not reported | 0 | (0.0) | 1 | (6.3) |
Type of treatment center** | ||||
Gynecologic clinic/tertiary care | 4 | (36.4) | 12 | (75.0) |
District hospital | 2 | (18.2) | 2 | (12.5) |
Primary care center/mobile unit | 8 | (72.7) | 1 | (6.3) |
Not reported | 1 | (9.1) | 1 | (6.3) |
Number of treatment centers | ||||
One | 5 | (45.5) | 16 | (100) |
Two or more | 5 | (45.5) | 0 | (0) |
Not reported | 1 | (9.1) | 0 | (0) |
Operator | ||||
Gynecologist, surgeon | 1 | (9.1) | 4 | (25.0) |
Doctor, general practitioner | 2 | (18.2) | 4 | (25.0) |
Nurse, "less qualified personnel" | 5 | (45.5) | 1 | (6.3) |
Not reported | 3 | (27.3) | 7 | (43.8) |
Number of operators | ||||
One | 1 | (9.1) | 1 | (6.3) |
Two to five | 1 | (9.1) | 5 | (31.3) |
Six or more | 5 | (45.5) | 0 | (0) |
Not reported | 4 | (36.4) | 10 | (62.5) |
Control of pain | ||||
No specific measure/Non-narcotic analgesics as needed | 5 | (45.5) | 0 | (0.0) |
Local anesthesia | 0 | (0.0) | 12 | (75.0) |
General anesthesia | 0 | (0.0) | 1 | (6.3) |
Not reported | 6 | (54.5) | 3 | (18.8) |
Antibiotherapy (pre-treatment) | ||||
Signs of cervicitis or STD | 3 | (27.3) | 2 | (12.5) |
All women | 4 | (36.4) | 3 | (18.8) |
Not reported | 4 | (36.4) | 11 | (68.8) |
*Cryotherapy, 11 studies; LEEP, 16 studies.
**Total percent add to more than 100%, because some studies are represented in more than one item category.
†Abnormalities such as polyp or cervical atrophy, for instance.
††Different gestational ages across studies.