Figure 7. Augmentation of c-RET tyrosine kinase activity in HM3KO cells by c-RET ligand (GDNF).

Expression of c-RET protein (A, B) and phosphorylated tyrosine 905 in c-RET (C, D) in HM3KO cells in the absence (A, C) or presence (B, D) of GDNF were examined by immunocytochemistry with anti-c-RET and anti-phosphorylated tyrosine 905 in c-RET antibodies using hematoxylin counterstaining (A–D).