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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Expert Opin Drug Deliv. 2010 May;7(5):631–645. doi: 10.1517/17425241003663236

Figure 9.

Figure 9

Selection of drugs for enhanced transscleral retinal drug delivery. Drugs that bind to pigment exhibit low permeability across the choroid layer and potentially retinal pigment epithelium, with the drug delivery differences being more dramatic for slow release systems. By selecting more permeable drugs, transscleral retinal delivery and hence effects can be potentially enhanced. Arrows indicate solute release or overall permeability. Tissue layers are not drawn to scale. Key: D1 – drug 1; D2 – drug 2.