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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Dec 17;34(3):432–442. doi: 10.1111/j.1530-0277.2009.01123.x

Table 2.

Effects of acute ethanol administration on serum levels of the neuroactive steroid precursors progesterone and deoxycorticosterone in male C57BL/6J and DBA/2J mice.

Progesterone Deoxycorticosterone
C57BL/6J
Saline 2.3 ± 0.6 7.7 ± 1.1
Ethanol 14.4 ± 3.6b 21.8 ± 5.3a
DBA/2J
Saline 1.3 ± 0.1 3.5 ± 0.6d
Ethanol 11.4 ± 2.2b 14.3 ± 1.7c

Ethanol (2 g/kg, 20% v/v in saline) or saline were administered i.p. 60 minutes before sacrifice. Levels are expressed as ng/ml and are average ± SEM of 7–8 mice per group.

a

p<0.05

b

p<0.005 and

c

p<0.0001 vs the respective saline-treated group; unpaired t-test.

d

p<0.005 vs the respective saline-treated C57BL/6J mice group; unpaired t-test.