Table 3.
−15 min | 60 min | 120 min | |
---|---|---|---|
Pregnenolone | 296.9 ± 28.9 | 262.4 ± 10.5 | 239.1 ± 14.9 |
3α,5α-THP | 124.8 ± 12.2 | 144.6 ± 12.6 | 134.4 ± 10.2 |
3α,5β-THP | 109.2 ± 4.5 | 105.1 ± 1.7 | 105.2 ± 2.1 |
3α,5α-THDOC | 63.0 ± 21.6 | 65.3 ± 19.6 | 45.1 ± 7.5 |
3α,5β-THDOC | n.d. | n.d. | n.d. |
3α,5α-Androsterone | 97.3 ± 12.0 | 63.4 ± 6.4 | 101.1 ± 22.9 |
3α,5β-Androsterone | 177.5 ± 88.7 | 275.8 ± 105.6 | 245.2 ± 71.9 |
3α,5α-Androstandiol | 34.9 ± 4.3 | 31.8 ± 2.4 | 34.6 ± 3.0 |
3α,5β-Androstandiol | 23.4 ± 1.4 | 27.3 ± 2.6 | 22.4 ± 1.2 |
Ethanol (0.8 g/kg, 16% w/v beverage solution) was consumed at time 0 and blood samples were collected 15 minutes before and 60 and 120 minutes from the start of ethanol consumption. Levels are expressed as pg/ml and are average ± SEM of eight subjects. 3α,5β-androsterone was detected only in 6/8 subjects 60 minutes after ethanol consumption; 3α,5β-androstandiol was detected only in 7/8 subjects 120 minutes after ethanol consumption. 3α,5β-THDOC was undetectable (n.d.).