TABLE 1. Comparison of human CerS.
| Name | Chromosomal location | Gene size (base pairs) | Protein size (Da) | Tissue mRNA expression profilea | Acyl chain-length specificitya |
|---|---|---|---|---|---|
| CerS1 | 19p12 | 25,837 | 39,536 | Brain, skeletal muscle, testis <4 molecules/ng of total RNA |
C18 |
| CerS2 | 1q21.2 | 9,792 | 44,876 | Kidney, liver 30–40 molecules RNA/ng of total RNA |
C20-C26 |
| CerS3 | 15q26.3 | 144,326 | 46,217 | Testis, skin <20 molecules/ng of total RNA |
C22-C26 |
| CerS4 | 19p13.2 | 53,046 | 46,399 | Low expression levels in all tissues, more in skin, leukocytes, heart, liver <8 molecules/pg of total RNA |
C18-C20 |
| CerS5 | 12q13.3 | 37,565 | 45,752 | Low expression levels in all tissues <2 molecules/ng of total RNA |
C16 |
| CerS6 | 2q24.3 | 318,394 | 44,890 | Low expression levels in all tissues <3 molecules/ng of total RNA |
C14 and C16 |