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Absence of CIN lesions in K14E7RbΔL/ΔL cervix. Representative sections of K14E7RbWT/WT and K14E7RbΔL/ΔL cervixes. Arrows, sites of cancer invasion into the dermis. In K14E7RbWT/WT cervix, cancer arises from epithelium containing many dysplastic changes (arrowheads), whereas in K14E7RbΔL/ΔL cervix, cancer is observed without any dysplastic changes elsewhere in the cervical epithelium.
