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. Author manuscript; available in PMC: 2011 Apr 13.
Published in final edited form as: Cancer Cell. 2010 Apr 13;17(4):400–411. doi: 10.1016/j.ccr.2009.12.050

Figure 1. The structure of the BCL6 BTB domain.

Figure 1

A: Structure of the 2:2 complex between the BCL6 BTB domain and the SMRT BBD peptide. The two chains of the BTB domain are shown in pink and blue and the two SMRT peptides are shown in stick representation with green carbon atoms. The SMRT 1423-1428 region is circled. B: View of the selected compounds docked to the BCL6 lateral groove pocket predicted by the CADD procedure along with the putative binding site represented by green transparent spheres. The compounds are stick representations based on the following color scheme: 28 (blue), 72 (magenta), 79 (red), 53 (yellow) and 55 (green). See also Figure S1 and Table S1.