TABLE II.
Mitochondrial DNA Lesion Number After MMS Treatmenta
Yeast strain | Mitochondrial DNA lesion number |
|||||
---|---|---|---|---|---|---|
0.0b | 0.025b | 0.050b | 0.075b | 0.100b | 0.150b | |
WT | 0.004 | 0.08 | 0.43 | 0.67 | 0.77 | 1.32 |
apn1Δ | 0.01 | 0.21 | 0.46 | 0.86 | 1.12 | 2.25 |
Lesion numbers were calculated per 10.0 kb per strand using the Poisson equation as described in the “Materials and Methods” section.
MMS dose (%).