Table 1.
Characteristics of Participants according to Clinical Categories of eGFRCKD-EPI
| Categories of eGFRCKD-EPI (ml/min/1.73m2) |
|||||
|---|---|---|---|---|---|
| >=120 | 90–119 | 60–89 | 30–59 | <30 | |
| Characteristic | (n = 716) | (n = 9,035) | (n = 3,931) | (n = 196) | (n = 27) |
| Age (y) | 49.4 ± 3.9 | 53.5 ± 5.5 | 55.5 ± 6.0 | 58.7 ± 5.3 | 56.4 ± 6.7 |
| Men | 188 (26) | 3,791 (42) | 1,956 (50) | 79 (40) | 7 (26) |
| Black race | 679 (95) | 2,267 (25) | 733 (19) | 63 (32) | 25 (93) |
| Educational level completed (n = 13,883) | |||||
| <12 yr | 253 (35) | 2,003 (22) | 798 (20) | 68 (35) | 16 (59) |
| 12 to 16 yr | 224 (31) | 3,771 (42) | 1,620 (41) | 69 (35) | 9 (33) |
| >16 yr | 238 (33) | 3,246 (36) | 1,507 (38) | 59 (30) | 2 (7) |
| Current smokers (n = 13,893) | 233 (33) | 2,545 (28) | 761 (19) | 45 (23) | 5 (19) |
| BMI (kg/m2) (n = 13,895) | 29.9 ± 6.9 | 27.4 ± 5.4 | 27.7 ± 4.8 | 28.5 ± 5.2 | 29.3 ± 5.5 |
| Diabetes mellitus (n = 13,882) | 145 (20) | 911 (10) | 383 (10) | 50 (26) | 15 (56) |
| Antihypertensive medication (n = 13,897) | 257 (36) | 2,220 (25) | 1,230 (31) | 124 (63) | 18 (67) |
| Systolic BP (mm Hg) (n = 13,900) | 126.6 ± 20.1 | 120.3 ± 18.4 | 121.3 ± 18.4 | 127.6 ± 22.3 | 153.5 ± 34.0 |
| Diastolic BP (mm Hg) (n = 13,900) | 79.2 ± 12.4 | 73.2 ± 11.1 | 73.9 ± 10.9 | 74.9 ± 12.2 | 80.2 ± 13.3 |
| LDL-C (mg/dL) (n = 13,625) | 127.4 ± 40.7 | 135.6 ± 38.5 | 140.4 ± 39.4 | 147.0 ± 45.4 | 153.3 ± 67.1 |
| HDL-C (mg/dL) (n = 13,814) | 57.2 ± 19.1 | 52.8 ± 17.1 | 50.3 ± 16.6 | 48.1 ± 16.6 | 48.4 ± 19.5 |
| Triglycerides (mg/dL) (n = 13,815) | 111.1 ± 81.8 | 127.1 ± 87.1 | 135.2 ± 91.6 | 165.1 ± 110.1 | 174.9 ± 145.1 |
| Left ventricular hypertrophy (n = 13,587) | 25 (4) | 157 (2) | 80 (2) | 9 (5) | 6 (22) |
| Carotid atherosclerosis (n = 13,473) | 46 (7) | 603 (7) | 338 (9) | 26 (14) | 7 (30) |
| Serum creatinine (mg/dL) | 0.61 ± 0.10 | 0.75 ± 0.13 | 0.96 ± 0.14 | 1.33 ± 0.24 | 7.00 ± 5.02 |
| eGFRCKD-EPI (ml/min/1.73m2) | 125.5 ± 5.3 | 102.1 ± 7.3 | 79.8 ± 7.4 | 53.0 ± 6.3 | 13.9 ± 10.1 |
| eGFRMDRD (ml/min/1.73m2) | 139.0 ± 19.4 | 99.2 ± 13.4 | 73.5 ± 6.8 | 50.5 ± 5.8 | 14.2 ± 9.9 |
Note: Values expressed as mean ± SD or number (percent). Conversion factors for units: LDL-C and HDL-C in mg/dL to mmol/L, ×0.02586; triglycerides in mg/DL to mmol/L, ×0.01129; creatinine in mg/dL to µmol/L, ×88.4; eGFR in ml/min/1.73m2 to mL/s/1.73 m2, ×0.01667.
Abbreviations and definitions: eGFRCKD-EPI, estimated glomerular filtration rate (eGFR) calculated using the CKD Epidemiology Collaboration (CKD-EPI) equation; eGFRMDRD, estimated glomerular filtration rate calculated using the Modification of Diet in Renal Disease (MDRD) Study equation; BP, blood pressure; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; MDRD, Modification of Diet in Renal Disease