Table 2. SUPREX Data and Screening Efficiency for AGTmi.
| Fragment number |
Molecular Weight (Da) |
C1/2SUPREX (M, GdmCl) |
SUPREX Curve Amplitude (Da) |
Average Standard Deviation (Da)a |
Z’-Factor | False Positives |
False Negatives |
|---|---|---|---|---|---|---|---|
| 1 | 3221 | 1.7 | 7.8 | 0.6 | 0.4 | 0 | 0 |
| 2 | 3334 | 1.7 | 8.4 | 0.6 | 0.5 | 0 | 0 |
| 3 | 3531 | 1.6 | 7.6 | 0.5 | 0.3 | 0 | 0 |
| 4 | 3965 | 1.7 | 7.3 | 0.7 | 0.0 | 0 | 1/30 (3%) |
| 5 | 4078 | 1.6 | 7.8 | 0.6 | 0.1 | 0 | 0 |
| 6 | 4564 | 1.3 | 8.0 | 1.0 | -0.3 | 0 | 1/30 (3%) |
| 7 | 5288 | 1.7 | 10.6 | 1.3 | 0.2 | 0 | 0 |
| 8 | 5404 | 1.5 | 8.6 | 1.3 | 0.3 | 0 | 0 |
| 9 | 5951 | 1.5 | 8.9 | 1.2 | 0.0 | 0 | 1/30 (3%) |
| 10 | 6197 | 1.4 | 10.1 | 1.3 | 0.1 | 1/30 (3%) | 0 |
| 11 | 6941 | 1.5 | 9.2 | 2.2 | -1.3 | 0 | 5/30 (17%) |
a
This value is the average of the standard deviations of the mass measurements from each point in a representative SUPREX curve.