Table 3.

Response data by treatment arm

	Arm A, concurrent R-EPOCH	Arm B, sequential EPOCH → R
Preamendment
No. treated/evaluable	17/17	18/16
CR or CRu	14 (82%)	11 (69%)
95% CI	57%-96%	41%-89%
CR + PR	16 (94%)	13 (82%)
Postamendment
No. treated/evaluable	34/31	37/37
CR or CRu	21 (68%)	18 (49%)
95% CI	49%-83%	32%-66%
CR + PR	26 (84%)	28 (76%)
All patients*	51/48	55/53
No. treated/evaluable
CR or CRu	35 (73%)	29 (55%)
95% CI	58%-85%	41%-68%
CR + PR	42 (88%)	41 (77%)

CRu indicates complete response (unconfirmed).

^*In an intention-to-treat analysis in all treated patients, the CR rates 69% in the concurrent arm (95% CI, 54%-81%) and 53% in the sequential arm (95% CI, 39%-66%).