Table 2.
Related, no. | Unrelated, no. | Combined no. (%) | |
---|---|---|---|
Nonfatal toxicity up to day 100* | |||
ALT elevation, grade IV | 8 | 5 | 13 (11) |
AST elevation, grade IV | 4 | 2 | 6 (5) |
Bilirubin elevation, grade IV | 4 | 4 | 8 (7) |
Serum creatinine, grade III | 3 | 3 | 6 (5) |
Reversible VOD | 7 | 1 | 8 (7) |
Hemorrhagic cystitis | 1 | 11 | 12 (10) |
Pericardial effusion | 3 | 0 | 3 (3) |
Subdural hematoma | 1 | 0 | 1 (1) |
Cause of death | |||
Related to relapse or progression | 21 | 10 | 31 (26) |
Related to transplantation | |||
Graft failure | 0 | 1 | 1 (1) |
VOD | 2 | 0 | 2 (2) |
Noninfectious pneumonia | 1 | 1 | 2 (2) |
Sepsis/bacterial infection | 2 | 1 | 3 (3) |
Hemorrhage | 2 | 2 | 4 (3) |
Refractory GVHD | 2 | 1 | 3 (3) |
Multisystem organ failure | 3 | 2 | 5 (4) |
ALT indicates alanine aminotransferase; and AST, aspartate aminotransferase.
Only highest-grade toxicities are presented.