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. 2010 Mar 2;115(16):3329–3340. doi: 10.1182/blood-2009-02-207225

Table 1.

MO sequences

Gene Target MO sequence
npm1a ATG/5′UTR TAATGTTATCCTCCATTTTTGCGCG
npm1a ATG/5′UTR 5-bp mismatch TAATcTTATCgTCgATTTTaGCcCG
npm1a Exon2-intron2 splice donor (2)* AAGAAACATCACATACCATTCTAAC
npm1a Exon3-intron3 splice donor TTATGACCAAGTCTACTTACACTTG
npm1b ATG/5′ UTR GACCCATCTGTTCGAGATCCATGTC
npm1b ATG/5′UTR 5-bp mismatch GAgCCATgTGTTCGAcATCgATcTC
npm1b Exon2-intron2 splice donor TCAAATATTCATCTTCCTCACCGAC
p53 ATG/5′UTR GCGCCATTGCTTTGCAAGAATTG
Std cont Human β-globin intron mutation CCTCTTACCTCAGTTACAATTTATA

Bold letters indicate the ATG codon; lowercase letters, mismatched residues; and Std cont, standard control.

*

(2) is the 1 working morpholino of 2 tested (supplemental Figure 1F, available on the Blood Web site; see the Supplemental Materials link at the top of the online article).