Table 1.

Biogenic amines.

Amine/metabolite	DOPAC		Dopamine		5-HIAA		5-HT		HVA
Genotype	WT	VGV	WT	VGV	WT	VGV	WT	VGV	WT	VGV
FRONTAL CORTEX
Saline	7.1 ± 1.8	10.2 ± 1.8	31.5 ± 10.4	68.2 ± 11.4*	10.4 ± 0.88	13.6 ± 1.7	25.9 ± 1.2	30.8 ± 2.2	6.7 ± 1.6	11.2 ± 1.8
SB206553	6.6 ± 0.8	15.6 ± 1.7	28.9 ± 6.7	34.2 ± 6.3	9.1 ± 0.7	16.0 ± 0.8	24.5 ± 2.4	20.0 ± 0.9	6.0 ± 0.7	13.9 ± 1.3
STRIATUM
Saline	15.3 ± 1.3	11.8 ± 0.9	111.9 ± 5.6	116.6 ± 7.5	19.4 ± 3.1	16.9 ± 1.8	26.6 ± 1.6	24.8 ± 1.4	17.1 ± 1.2	27.5 ± 1.5
SB206553	14.39 ± 1.4	24.1 ± 1.0	110.8 ± 10.7	95.0 ± 15.1	18.9 ± 0.7	26.2 ± 1.1	25.9 ± 1.8	25.4 ± 0.6	16.2 ± 1.3	16.1 ± 1.1

The results are presented as means ± SEM (n = 5). *Significantly different from WT, p < 0.01. Data were analyzed with ANOVAs.