Table 1.
Characteristics of the study subjects in the proteinuria analyses.
| Variable | ACTG 384 N=576 | ACTG A5095/ALLRT N=436 | Total N=1012 |
|---|---|---|---|
| Age, yrs | 35 (30, 42) | 37 (32, 43) | 36 (31, 43) |
| Male n, (%) | 472 (82) | 375 (86) | 846 (84) |
| Race/ethnicity, n (%) | |||
| Black, non-Hispanic | 219 (38) | 126 (29) | 346 (34) |
| White, non-Hispanic | 265 (46) | 205 (47) | 472 (47) |
| Hispanic | 81 (14) | 96 (22) | 176 (17) |
| CD4 cell count/μL | |||
| Median | 275 (100, 452) | 244 (109, 374) | 262 (103, 425) |
| <200, n (%) | 216 (38) | 180 (41) | |
| Log10 HIV-1 RNA/mL | 4.95 (4.35, 5.54) | 4.75 (4.38, 5.33) | 4.85 (4.37, 5.47) |
| Hemoglobin, g/dL | 13.7 (12.5, 14.9) | 13.8 (12.5, 14.8) | 13.7 (12.5, 14.8) |
| Hypertension, n (%) | 36 (6) | 36 (8) | 72 (7) |
| Diabetes mellitus, n (%) | 9 (2) | 16 (4) | 25 (2) |
| Viral hepatitis B or C co-infection, n (%) | 38 (7) | 68 (16) | 106 (10) |
| Creatinine clearance, mL/min | |||
| Median | 113 (95, 138) | 121 (99, 143) | 116 (96, 141) |
| <90, n (%) | 104 (18) | 72 (17) | 176 (18) |
| Proteinuria, n (%) | |||
| ≥1+ | 39 (7) | 34 (8) | 73 (7) |
| ≥2+ | 17 (3) | 7 (2) | 24 (2) |
| ≥3+ | 6 (1) | 1 (<1) | 7 (<1) |
| %CD8+/CD38+/HLA-DR+ | 49 (38, 60) | 53 (37, 64) | 50 (37, 62) |
NOTE. All values are presented as median (25th percentile, 75th percentile) unless otherwise specified.