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. 2010 Apr 22;5(4):e10306. doi: 10.1371/journal.pone.0010306

Figure 7. WIN55,212-2 produces different effects on EPSCs at the PP and SC.

Figure 7

A1. Representative traces of paired-EPSCs recorded from a rat hippocampal CA1 pyramidal neuron in response to independent PP and SC stimuli in the absence and presence of WIN (5 µM). A2. Mean values of paired-pulse ratio (PPR) at the PP and SC in the absence and presence of WIN. A3. Time courses of WIN-induced changes in EPSCs at the PP and SC. A4. Mean values of EPSCs averaged from 20 to 25 min following WIN application. *P<0.05, **P<0.01 compared with PP. B1. Representative traces of paired-EPSCs recorded in slices treated with RIM (2 µM) in the absence and presence of WIN (5 µM). B2. Mean values of PPR at the PP and SC in the absence and presence of WIN+RIM. B3. Time courses of WIN-induced changes in EPSCs at the PP and SC in the presence of RIM. B4. Mean values of EPSCs averaged from 20 to 25 min following WIN application in RIM-treated slices. Scale bars: 200 pA/100 msec.