Table 2.

Anthrometric characteristics in obese and normal-weight children and adolescents stratified according to TMEM18 rs6548238 and rs7561317 genotype.

rs6548238	CC	CT	TT	P
Normal-weight, n = 523
Age (years)	17.1 ± 0.9	16.9 ± 0.8	17.0 ± 0.5	0.126
Weight (kg)	63.5 ± 9.9	63.5 ± 10.1	65.2 ± 9.6	0.247
Length (m)	1.73 ± 0.08	1.73 ± 0.09	1.73 ± 0.09	0.651
BMI SDS	0.139 ± 0.565	0.184 ± 0.630	0.158 ± 0.375	0.921
Obese, n = 500
Age (years)	12.2 ± 3.3	12.6 ± 2.9	13.2 ± 2.5	0.203
Birth length (cm)	50.0 ± 2.9	50.4 ± 2.5	52.1 ± 1.6	0.048
Birth weight (g)	3465 ± 721	3627 ± 641	3879 ± 225	0.077
Length (m)	1.66 ± 0.14	1.58 ± 0.16	1.58 ± 0.18	0.674
Weight (kg)	109.6 ± 31.5	90.4 ± 28.5	91.5 ± 29.1	0.920
BMI SDS	6.3 ± 0.9	5.5 ± 1.6	5.8 ± 1.5	0.073
P-Glucose (mmol/l)	4.5 ± 0.7	4.3 ± 0.6	4.4 ± 0.9	0.512
fS-Insulin (mmol/l)	118.2 ± 71.3	113.8 ± 74.5	92.6 ± 44.3	0.503
Triglycerides (mmol/l)	0.82 ± 0.81	0.82 ± 0.97	0.57 ± 0.53	0.944
Cholesterol (mmol/l)	3.73 ± 0.85	3.84 ± 0.86	3.43 ± 0.53	0.482
rs7561317	GG	GA	AA	P
Normal-weight, n = 523
Age (years)	17.1 ± 0.9	16.9 ± 0.8	17.1 ± 0.5	0.175
Weight (kg)	63.4 ± 9.9	63.6 ± 9.9	65.2 ± 9.6	0.335
Length (m)	1.72 ± 0.09	1.73 ± 0.09	1.73 ± 0.09	0.708
BMI SDS	0.139 ± 0.567	0.181 ± 0.629	0.158 ± 0.374	0.780
Obese, n = 500
Age (years)	12.2 ± 3.3	12.6 ± 2.9	13.3 ± 2.5	0.191
Birth length (cm)	49.9 ± 2.9	50.4 ± 2.4	52.1 ± 1.6	0.032
Birth weight (g)	3469 ± 723	3614 ± 644	3879 ± 225	0.121
Length (m)	1.66 ± 0.14	1.58 ± 0.16	1.58 ± 0.18	0.792
Weight (kg)	109.6 ± 31.5	90.1 ± 27.8	91.5 ± 29.3	0.859
BMI SDS	6.3 ± 0.9	5.5 ± 1.6	5.8 ± 1.5	0.038
P-Glucose (mmol/l)	4.5 ± 0.7	4.3 ± 0.6	4.4 ± 0.9	0.362
fS-Insulin (mmol/l)	117.7 ± 71.4	115.4 ± 74.6	92.6 ± 44.3	0.713
Triglycerides (mmol/l)	0.82 ± 0.80	0.81 ± 0.96	0.57 ± 0.53	0.882
Cholesterol (mmol/l)	3.73 ± 0.86	3.83 ± 0.86	3.43 ± 0.53	0.683

Data are means and SD divided into genotype groups. P indicates p-values adjusted for

significant covariates.