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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Trends Cardiovasc Med. 2009 Oct;19(7):213–220. doi: 10.1016/j.tcm.2009.12.004

Figure 1.

Figure 1

Echocardiography of 170 WT and mCAT C57Bl/6 mice in a longevity cohort. (A) Left ventricular mass index (LVMI=LVM/body weight), (B) systolic function measured by percentage of fractional shortening (FS), (C) diastolic function measured by tissue Doppler imaging Ea/Aa, (D) the proportion of mice with diastolic dysfunction, defined as Ea/Aa<1, (E) left atrial dimension and (F) the myocardial performance index were analyzed. The linear trends across ages in WT mice were significant for all parameters (P<0.05 for all). The beneficial effect of mCAT vs. WT was analyzed by the interaction term between genotype and the age trend, and was significant in all cases (P <0.01 for all except fractional shortening, P =0.03). Data reanalyzed from (Dai et al. 2009)