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Urinary albumin to creatinine ratio (UACR) of normoglycemic control rats (n = 8), and streptozotocin (STZ)-induced diabetic rats (DM; n = 10) treated with PRR blocker (DM + PRRB; n = 10), valsartan (DM + VAL; n = 10), or PRRB plus valsartan (DM + PRRB + VAL; n = 9) at baseline (open bars) and after two weeks of STZ-induction of diabetes and drug treatment (solid bars). Data are mean ± SEM. *P < 0.05 vs. control; #P < 0.05 vs. DM.
