Table 1.
Body weight, blood glucose, 24-h urine output, and left kidney mass index at the end of two weeks study in normoglycemic control rats, diabetic non-treated rats (DM), and diabetic rats treated with (pro)renin receptor blocker (DM + PRRB), valsartan (DM + VAL), or PRRB plus valsartan (DM + PRRB + VAL).
Control (n=8) |
DM (n=10) |
DM+PRRB (n=10) |
DM+VAL (n=10) |
DM+PRRB+VAL (n=9) |
|
---|---|---|---|---|---|
Body Weight g | 331±5 | 264±14* | 274±9* | 273±5* | 278±9* |
Blood Glucose mg/dl | 85±4 | 461±23* | 452±15* | 421±9* | 426±20* |
Urine Volume ml/d | 23±1 | 198±7* | 199±9* | 198±19* | 207±5* |
Left kidney mass index mg/g |
3.4±0.1 | 5.6±0.2* | 5.2±0.2* | 5.3±0.1* | 5.3±0.2* |
Data are mean ± SEM.
P < 0.05 versus control.