Table 1.
Baseline Characteristics of the Study Patients by Type of cART and by Gender
| Characteristics | NNRTI (n = 161) | PI/r (n = 126) | p | Males (n = 220) | Females (n = 67) | p |
|---|---|---|---|---|---|---|
| Male gender (%) | 130 (81) | 85 (68) | 0.02 | |||
| Female gender (%) | 29 (18) | 37 (30) | ||||
| cART = NNRTI | 130 (60) | 29 (44) | 0.02 | |||
| High school or higher education (%) | 113 (70) | 91 (72) | 0.92 | 166 (76) | 42 (63) | 0.14 |
| Mean age (SD) | 39 (9.7) | 40 (9.6) | 0.88 | 38 (9.5) | 41 (9.9) | 0.06 |
| Mean BMI (SD) | 24 (4.4) | 24 (4.1) | 0.43 | 23 (4.1) | 25 (5.3) | 0.02 |
| Ethnicity | 0.18 | <0.0001 | ||||
| African American (%) | 103 (64) | 74 (59) | 142 (65) | 39 (59) | ||
| White (%) | 18 (11) | 20 (16) | 33 (15) | 5 (8) | ||
| Black African (%) | 14 (9) | 15 (12) | 13 (6) | 17 (26) | ||
| Latino (%) | 24 (15) | 11 (9) | 31 (14) | 4 (6) | ||
| HIV transmission risk factor | 0.47 | <0.0001 | ||||
| MSM (%) | 74 (46) | 50 (40) | 124 (57) | NA | ||
| IVDU (%) | 14 (9) | 15 (12) | 19 (9) | 10 (15) | ||
| Heterosexual (%) | 70 (44) | 57 (46) | 71 (33) | 56 (84) | ||
| HIVRNA <100,000 copies/ml (%) | 36 (22) | 37 (29) | 0.4 | 54 (27) | 19 (28) | 0.89 |
| Mean CD4+ cells/mm3 | 47 | 37 | 0.65 | 38 | 53 | 0.06 |
| CD4+ <100 cell/mm3 (%) | 96 (60) | 94 (75) | 0.003 | 148 (68) | 42 (63) | 0.29 |
| Drug abuse (%) | 30 (19) | 31 (25) | 0.19 | 43 (20) | 21 (32) | 0.04 |
| Major psychiatric illness (%) | 7 (4) | 4 (3) | 0.76 | 10 (5) | 1 (2) | 0.26 |
| Depression (%) | 36 (23) | 34 (27) | 0.32 | 51 (24) | 20 (30) | 0.24 |
| Hepatitis C antibody positive (%) | 17 (11) | 15 (12) | 0.64 | 21 (10) | 11 (17) | 0.12 |
| Hepatitis B surface antigen positive (%) | 28 (18) | 17 (14) | 0.4 | 38 (17) | 7 (11) | 0.17 |
| OI at baseline (%) | 81 (50) | 66 (53) | 0.6 | 107 (50) | 40 (60) | 0.14 |
| CDC Stage C3 (%) | 80 (50) | 64 (51) | 0.67 | 107 (49) | 38 (57) | 0.23 |
| NRTI used | 0.7 | 0.19 | ||||
| Zidovudine/lamivudine (%) | 73 (46) | 66 (53) | 101 (46) | 38 (57) | ||
| Tenofovir/emtricitabine (%) | 65 (41) | 34 (27) | 82 (37) | 17 (26) | ||
| Other (%) | 21 (13) | 22 (18) | 38 (17) | 11 (17) |